氏名
時田佳治
最終学歴（学位）
群馬大学大学院医学系研究科博士後期課程修了（博士（保健学））
職歴
2010年4月―2021年3月
群馬大学医学部保健学科検査技術学専攻 助教
（2011年4月から大学院保健学研究科に改組）
2013年7月―2021年3月
群馬大学多職種連携教育研究研修センター（WHO協力センター） （兼任）
2016年10月―2017年3月
World Health Organization, HQ, Service Delivery and Safety Department, Professional Volunteer
2017年12月―2021年3月
群馬大学食健康科学教育研究センター（兼任）
2018年4月―現在に至る
女子栄養大学栄養科学研究所客員准教授
2021年4月―現在に至る
群馬医療福祉大学医療技術学部臨床検査学専攻 准教授
研究テーマ
活性硫黄分子種や血清脂質に着目した生活習慣病予防のための研究
主要な学術論文・業績
- 1: Nakajima K, Tokita Y, Tanaka A. Atherogenic postprandial remnant lipoproteins-a causal lipoproteins for the initiation of obesity and atherosclerosis. J Lab Precis Med 2020;5:19.
- 2: Lee B, Phrasisombath K, Shinozaki H, Vangkonevilay P, Bouphavanh K,Prabouasone K, Sounthavong O, Tokita Y, Makino T, Matsui H, Saitoh T, Tozato F,Kama A, Watanabe H. Key factors affecting the integration of interprofessional education into human resources for health reform: a Lao People’s Democratic Republic case study. J Interprof Care. 2019 Jul-Aug;33(4):356-360.
- 3: Nakajima K, Tokita Y, Tanaka A, Takahashi S. The VLDL receptor plays a key role in the metabolism of postprandial remnant lipoproteins. Clin Chim Acta. 2019 Aug;495:382-393
- 4: Watanabe H, Makino T, Tokita Y, Kishi M, Lee B, Matsui H, Shinozaki H, Kama A. Changes in attitudes of undergraduate students learning interprofessional education in the absence of patient safety modules: evaluation with a modified T-TAQ instrument. J Interprof Care. 2019 Nov-Dec;33(6):689-696.
- 5: Nakajima K, Koyama I, Watanabe M, Nakamura M, Miyamoto Y, Tokita Y, Sakamaki K, Yatsuzuka SI, Shimomura Y. Comparison of the International Federation of Clinical Chemistry and Japan Diabetes Society reference methods for conversion to the National Glycohemoglobin Standardization Program values. Ann Clin Biochem. 2019 Jul;56(4):508-514.
- 6: Nakajima K, Tokita Y, Tanaka A. Hypothesis II: The majority of VLDL-apoB48 remnants in postprandial plasma are derived from the liver, not from the intestine. Clin Chim Acta. 2019 Mar;490:12-16.
- 7: Nakajima K, Tokita Y, Tanaka A. Hypothesis: Postprandial remnant lipoproteins are the causal factors that induce the insulin resistance associated with obesity. Clin Chim Acta. 2018 Oct;485:126-132.
- 8: Tokita Y, Hirayama M, Nakajima K, Tamaki K, Iha M, Nagamine T. Detection of Fucoidan in Urine after Oral Intake of Traditional Japanese Seaweed, Okinawa mozuku (Cladosiphon okamuranus Tokida). J Nutr Sci Vitaminol. 2017;63(6):419-421.
- 9: Makino T, Lee B, Matsui H, Tokita Y, Shinozaki H, Kanaizumi S, Abe Y, Saitoh T, Tozato F, Igarashi A, Sato M, Ohtake S, Tabuchi N, Inagaki M, Kama A, Watanabe H. Health science students’ attitudes towards healthcare teams: A comparison between two universities. J Interprof Care. 2018 Mar;32(2):196-202.
- 10: Aruga M, Tokita Y, Nakajima K, Kamachi K, Tanaka A. The effect of combined diet and exercise intervention on body weight and the serum GPIHBP1 concentration in overweight/obese middle-aged women. Clin Chim Acta. 2017 Dec;475:109-115.
- 11: Tokita Y, Maejima Y, Shimomura K, Takenoshita S, Ishiyama N, Akuzawa M, Shimomura Y, Nakajima K. Non-alcoholic Fatty Liver Disease Is a Risk Factor for Type 2 Diabetes in Middle-aged Japanese Men and Women. Intern Med. 2017;56(7):763-771.
- 12: Nakajima K, Tokita Y, Sakamaki K, Shimomura Y, Kobayashi J, Kamachi K,Tanaka A, Stanhope KL, Havel PJ, Wang T, Machida T, Murakami M. Triglyceride content in remnant lipoproteins is significantly increased after food intake and is associated with plasma lipoprotein lipase. Clin Chim Acta. 2017 Feb;465:45-52.
- 13: Ishiyama N, Sakamaki K, Shimomura Y, Kotani K, Tsuzaki K, Sakane N, Miyashita K, Fukamachi I, Kobayashi J, Stanhope KL, Havel PJ, Kamachi K, Tanaka A, Tokita Y, Machida T, Murakami M, Nakajima K. Lipoprotein lipase does not increase significantly in the postprandial plasma. Clin Chim Acta. 2017 Jan;464:204-210.
- 14: Sakamaki K, Maejima Y, Tokita Y, Masamura Y, Kumamoto K, Akuzawa M, Nagano N, Nakajima K, Shimomura K, Takenoshita S, Shimomura Y. Impact of the Visceral Fat Area Measured by Dual Impedance Method on the Diagnostic Components of Metabolic Diseases in a Middle-aged Japanese Population. Intern Med. 2016;55(13):1691-6.
- 15: Lee B, Shinozaki H, Bouphavanh K, Tokita Y, Makino T, Matsui H, Saitoh T,Tozato F, Watanabe H. A plan for embedding an interprofessional education initiative into an existing programme in a Southeast Asian university. J Interprof Care. 2016 May;30(3):401-3.
- 16: Kururi N, Tozato F, Lee B, Kazama H, Katsuyama S, Takahashi M, Abe Y, Matsui H, Tokita Y, Saitoh T, Kanaizumi S, Makino T, Shinozaki H, Yamaji T, Watanabe H. Professional identity acquisition process model in interprofessional education using structural equation modelling: 10-year initiative survey. J Interprof Care. 2016;30(2):175-83.
- 17: Makino T, Nozaki S, Lee B, Matsui H, Tokita Y, Shinozaki H, Watanabe H. Attitudes of nursing school deans toward interprofessional education in Western Pacific Region countries. J Interprof Care. 2015;29(5):518-9.
- 18: Kikkawa K, Nakajima K, Shimomura Y, Tokita Y, Machida T, Sumino H, Murakami M. Small dense LDL cholesterol measured by homogeneous assay in Japanese healthy controls, metabolic syndrome and diabetes patients with or without a fatty liver. Clin Chim Acta. 2015 Jan 1;438:70-9.
- 19: Kururi N, Makino T, Kazama H, Tokita Y, Matsui H, Lee B, Kanaizumi S, Abe Y,Uchida Y, Asakawa Y, Shinozaki H, Tozato F, Watanabe H. Repeated cross-sectional study of the longitudinal changes in attitudes toward interprofessional health care teams amongst undergraduate students. J Interprof Care. 2014 Jul;28(4):285-91.
- 20:Nagamine T, Tokita Y, Kikuchi H, Akutsu T, Tomioka S, Kamiya T, Satoh T, Kohka M. Establishment of erythrocyte samples for in-air micro-PIXE analysis and its application to erythrocytes in hemodialysis patients. International Journal of PIXE. 2014; 22:249-258
- 21: Yatsuzuka S, Shimomura Y, Akuzawa M, Ando Y, Kobayashi I, Nakano T, Tokita Y, Nagamine T, Ono H, Tanaka A, Schaefer E, Nakajima K. Plasma adiponectin is a more specific marker of fatty liver than a marker of metabolic syndrome in Japanese men. Ann Clin Biochem. 2014 Jan;51(Pt 1):68-79.
- 22: Ito N, Shibuguchi N, Ishikawa R, Tanaka S, Tokita Y, Nakajima-Shimada J,Hosaka K. Identification of alkylbenzene sulfonate surfactants leaching from an acrylonitrile butadiene rubber as novel inhibitors of calcineurin activity. Biosci Biotechnol Biochem. 2013;77(5):954-60.
- 23: Saito H, Nakazato K, Kato M, Kodaira T, Akutsu T, Tokita Y, Suzuki K, Nagamine T, Nakajima K. Determination of metallothionein-3 by a competitive enzyme-linked immunosorbent assay in experimental animals. J Toxicol Sci. 2013 Feb;38(1):83-91.
- 24: Nakajima K, Nakano T, Tokita Y, Nagamine T, Yatsuzuka S, Shimomura Y, Tanaka A, Sumino H, Nara M, Machida T, Murakami M. The characteristics of remnant lipoproteins in the fasting and postprandial plasma. Clin Chim Acta. 2012 Jul 11;413(13-14):1077-86.
- 25: Nakajima K, Nakano T, Tokita Y, Nagamine T, Inazu A, Kobayashi J, Mabuchi H, Stanhope KL, Havel PJ, Okazaki M, Ai M, Tanaka A. Postprandial lipoprotein metabolism: VLDL vs chylomicrons. Clin Chim Acta. 2011 Jul 15;412(15-16):1306-18.
- 26: Nakano T, Tanaka A, Okazaki M, Tokita Y, Nagamine T, Nakajima K. Particle size of apoB-48 carrying lipoproteins in remnant lipoproteins isolated from postprandial plasma. Ann Clin Biochem. 2011 Jan;48(Pt 1):57-64.
- 27: Nakano T, Tokita Y, Nagamine T, Tanaka A, Okazaki M, Yatsuzuka S, Tamei N, Shimomura Y, Ando Y, Akamatsu S, Fujita MQ, Nakajima K. Measurement of serum remnant-like lipoprotein particle-triglyceride (RLP-TG) and RLP-TG/total TG ratio using highly sensitive triglyceride assay reagent. Clin Chim Acta. 2011 Jan 14;412(1-2):71-8.
- 28: Nakajima K, Kodaira T, Kato M, Nakazato K, Tokita Y, Kikuchi H, Sekine H, Suzuki K, Nagamine T. Development of an enzyme-linked immunosorbent assay for metallothionein-I and -II in plasma of humans and experimental animals. Clin Chim Acta. 2010 May 2;411(9-10):758-61.
- 29: Tokita Y, Nakajima K, Mochida H, Iha M, Nagamine T. Development of a fucoidan-specific antibody and measurement of fucoidan in serum and urine by sandwich ELISA. Biosci Biotechnol Biochem. 2010;74(2):350-7.
［その他］
- 1: 時田佳治、李範爽、牧野孝俊、松井弘樹、篠崎博光、蒲章則、渡邊秀臣. WHO協力センター寄稿 西太平洋地域における多職種連携教育の普及と推進に向けて. 目で見るWHO. 2019; 68: 20-21.
- 2: 時田佳治. 食後血中レムナントリポプロテインの挙動解析. The Kitakanto Medical Journal. 2019; 69: 69-70.
- 3: 時田佳治. 医療の質を改善するためのWHOの役割. 目で見るWHO. 2017; 63:28-30.
- 4: Tokita Y, Kikuchi H, Satoh T, Kamiya T, Arakawa K. Preparation of human erythrocyte for in-air micro-PIXE analysis. JAEA-Review. 2011; 65:117
- 5: 時田佳治、金泉志保美、齋藤貴之、牧野孝俊、松井弘樹、久留菜菜、李範爽、安部由美子、浅川康吉、外里冨佐江、篠崎博光、渡邊秀臣. 群馬大学のIPEトレーニングコースの紹介. 保健医療福祉連携. 2017; 10: 119-127.
- 6: Yoshiharu Tokita. Keynote 2 “”Development of interprofessional education for parient safey in Gunma univerity”” The 1st PSU-IPE conference in Helath Sciences. Thailand. 2019.
- 7: Yoshiharu Tokita. Plenary session 3- IPEC development from global concensus to practice. “”IPEC and quality improvement of healthcare in the UHC era””. The 1st Asia-Pacific interprofessional education and collaboration conference. Indonesia. 2017.
- 8: 特別論文「過体重および肥満成人における炭水化物制限食の低比重リポタンパクコレステロール値に与える影響：系統的レビューとメタ解析」. 国際生命科学研究機構（女子栄養大学出版部）、栄養学レビュー. 2019;41-65.
社会貢献
日本未病学会 評議員
保健医療福祉連携教育学会 編集委員
Member of Global Patient Safety Network
主要な獲得外部資金/受賞歴
外部資金
・科学研究費補助金 基盤研究（C）
『大腸における海産物由来硫酸化多糖類からの活性硫黄分子種の産生評価』（代表者）
・科学研究費補助金 基盤研究（B）
『WHOとの連携に基づくチーム医療教育効果に対する２施設縦断研究とアジア展開』（分担者）
受賞歴
2018年 北関東医学会奨励賞
『レムナントリポプロテインの挙動解析ならびにその関連疾患の予防に関する研究』